The CASE scale was validated (Figure 3), and the results showed that the CASE score was positively correlated with the mRS score in total AE (r = 0.849, P < 0.001), NMDAR encephalitis (r = 0.868, P < 0.001), LGI1 encephalitis (r = 0.741, P < 0.001) and GABABR encephalitis (r = 0.778, P < 0.001). The gene discussed is LGI1; the disease is encephalitis.