Albeit IFNγ expression was increased in CD69−CD103− and CD69+CD103+ CD4+ T-cell subsets during DSS-induced colitis, only small percentages of CD69−CD103− CD4+ T cells and CD69+CD103+ CD4+ TRM cells expressed IFNγ (Figure 2F; Supplementary Figure 4B). Here, CD4 is linked to colitis.