could show that treatment of senescent glioblastoma U87-MG cells and senescent T-cells derived from peripheral blood of GBM patients with the senolytic drug longevity-associated variant (LAV) of the bactericidal/permeability-increasing fold-containing family B member 4 (LAV-BPIFB4) reduced the senescent phenotype in both U87-MG cells and patient-derived PBMCs (29). Here, BPIFB4 is linked to glioblastoma.