To specifically examine the effector function of NKp46+ ILC3s during infection and to rule out all influence from other immune cells, we isolated the equal number of highly purified NKp46+ ILC3s from control and ThPOK-deficient mice and adoptively transferred them into NCG (Rag2-/- Il2rg-/-) mice, in which no ILCs or T/B cells exist. The gene discussed is RAG2; the disease is infection.