PPARG and Hepatic fibrosis: Hepatic fibrosis is regulated by a series of epigenetic relays that include down-regulation of miR-132, binding of the methyl-CpG binding protein 2 (MeCP2) to the 5’ end of the PPAR-γ-producing gene (PPARG), and activation of the enhancer of zeste homolog 2 (EZH2) (277) (Table 5).