TNF and rheumatoid arthritis: Tumor necrosis factor-α (TNF-α), interleukin-17 (IL-17), interleukin-6 (IL-6), interleukin-4 (IL-4) antibodies and other drugs have been proven useful in treating rheumatoid arthritis (RA), psoriasis, cytokine release syndrome (CRS), atopic dermatitis (AD) and other autoimmune diseases (15–18).