AIM2 and pulmonary fibrosis: In contrast, AIM2 stimulation in PBMCs from patients who presented lung fibrosis-like changes significantly increased (p=0.01) IL-1α levels (Figure 1B, ctr: 34.75 ± 5.42 pg/ml vs PolydA:dT: 81.6 ± 16.5 pg/ml).