Other non-HLA genetic factors involved in autoimmunity are small nucleotide polymorphisms (SNP) in immune associated genes, such as IL7R, SH2B3, CTLA4, BACH2, CLEC16A and CD226, and the latter are involved in both MS and T1D risk (5, 6, 9, 131–134). Here, IL7R is linked to myeloid sarcoma.