In detail, the trafficking abilities of T cell, CD4 T cell, CD8 T cell, Th1 cell, DC, NK cell, and Th2 cell to tumors are stronger in the low-MRGPI patients than those in the high-MRGPI patients, while the trafficking abilities of Neutrophil and Treg cell to the tumor are weaker in the low-MRGPI patients (Figure 3D). Here, CD4 is linked to neoplasm.