Against the background of gene sets included in the hallmark dataset, the gene set enriched in the high-MRGPI subgroup contains pathways related to tumor epithelial-mesenchymal transition (EMT) conversion, glycolysis, and hypoxia (Figure 2B), while the gene set of the low-MRGPI sample is enriched in interleukin-2 (IL-2) channels (Figure 2C; p < 0.05, FDR <0.25). Here, IL2 is linked to neoplasm.