Therefore, the MRGPI of patients’ tumor samples was calculated by the formula: MRGPI = the expression level of HPRT1 * (0.57) + the expression level of AGPAT4 * (0.24) + the expression level of AMY2B * (-0.50) + the expression level of ACADL * (0.59) + the expression level of CKM * (0.07) + the expression level of PLA2G2D * (-0.21) + the expression level of ADA * (0.21). The gene discussed is HPRT1; the disease is neoplasm.