In response to infection, in male mice, the TACC2, BUB1B, ATP5MC3, and MYO1E, and in female mice, the CAP1, MRPL2, COX5A, KLHL21, PDIA6, TSPO, and USP14 had direct interaction with TP-53 (Supplementary Figure 1). The gene discussed is USP14; the disease is infection.