In vivo, in a double xenograft model, photoactivating BNP prevented the growth of both irradiated and non-irradiated neoplastic lesions and induced a significantly larger amount of both CD4+ and CD8+ T cells in the spleen and in the non-irradiated tumor, together with active secretion of IFN-ɣ (58). Here, IFNA1 is linked to neoplasm.