TLR4 and Sepsis: Figure 7A shows the expressions of HMOX1, MAPK14, and TLR4 in the sepsis and control groups (all P < 0.001). The AUROC of HMOX1 (Figure 7B), MAPK14 (Figure 7C), and TLR4 (Figure 7D) in the diagnosis of sepsis were 0.770, 0.941, and 0.774 respectively. The specificity and PPV were all more than 0.9 (Figure 7E).