CD274 and Sepsis: In addition, there was also a clinical trial of PD-L1 monoclonal antibody in the treatment of sepsis (a phase 1b/2a, randomized, double-blinded, placebo-controlled, multicenter study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of BMS-936559 in subjects with severe sepsis; NCT02576457) (32).