CD163 and schizophrenia: We found mRNA levels of the macrophage marker CD163 were significantly elevated in schizophrenia cases compared to control cases [main effect of diagnosis: F(1,127) = 4.00, p = 0.048], and were also greatly elevated in individuals with high inflammation compared to those with low inflammation [main effect of inflammation: F(1,127) = 24.08, p = 2.78E-06] (Figure 2C).