CCL2 and schizophrenia: Given that the macrophage chemoattractant CCL2 promotes pro-inflammatory “M1-like” polarization in human macrophages (Sierra-Filardi et al., 2014), we also expected that CCL2 mRNA to be increased in high inflammation schizophrenia and to be positively related to proinflammatory macrophage markers and negatively related to anti-inflammatory macrophage markers (Yang et al., 2011; Gschwandtner et al., 2019).