First identified by Folkman in 1971 as a controller of tumor growth, VEGFs are a family of peptides that comprise five members (VEGF‐A, VEGF‐B, VEGF‐C, VEGF‐D, and placental growth factor), each encoded by five distinct multiexon genes, of which VEGF‐A plays the major role in angiogenesis and vascular permeability (Bates et al., 2018; Dvorak et al., 1995; Ferrara & Davis‐Smyth, 1997). The gene discussed is VEGFA; the disease is neoplasm.