The results showed that TXNIP expression was lower in several cancer groups than in normal tissues, including breast cancer, colorectal cancer (CRC), head and neck cancer, lung cancer, ovarian cancer, sarcoma (SARC), lymphoma, liver cancer or bladder cancer (Fig. 1B, all P < 0.05), and more detailed results were summarized in Additional file 8: Table S1. Here, TXNIP is linked to colorectal cancer.