In addition to ovarian cancer, MLK3 also plays an essential role in controlling cell proliferation, migration, invasion, and metastasis in other type of cancers, including triple-negative breast cancer, gastric cancer, liver cancer, colorectal cancer, and melanoma (6, 7, 8, 9, 10, 11, 12, 13, 14, 15). This evidence concerns the gene MAP3K11 and ovarian carcinoma.