Mixed lineage kinase 3 (MLK3) is a serine/threonine mitogen-activated protein kinase (MAPK) kinase kinase (MAP3K) (1, 2, 3) that is required for invasion and proliferation of ovarian cancer cells, and its activity and expression are higher in ovarian cancer cells than normal ovarian epithelial cells (4, 5, 6). Here, MAP3K11 is linked to ovarian carcinoma.