We used the data of 140 patients to analyze the correlation between PD-1/PD-L1 expression and clinicopathological features of IBC and found that PD-L1 expression in TC was related to the age, menopausal status, lymph node metastasis, lymphovascular invasion, TNM clinical stage, and ER expression (all P < 0.05). This evidence concerns the gene CD274 and metastatic malignant neoplasm in the lymph nodes.