In LUAD, 13 differentially expressed LCTs corresponding to 13 genes were discovered (Fig. 2E, right, Table S12 and Methods), among which five events (L1-MCM3, L1-PHF20, L1-INPP4B, L1-SLC44A5, L1-SUGCT) are overlapped with those detected in LUSC suggesting their common and unified role in carcinogenesis of NSCLC. The gene discussed is MCM3; the disease is non-small cell lung carcinoma.