FGGY and neoplasm: The increased secretion levels of 12S-HETE was detected in H520OV−L1−FGGY vs H520OV−CTRL cell lines (Fig. 4G) and further validated in 50 LUSC tissues compared to matched adjacent normal tissues (Table S20-S21) as well as L1-FGGY+ vs FGGY− tumor tissues (Fig. 4G).