SLC2A10 and obesity due to melanocortin 4 receptor deficiency: We also studied the effects of GLUT10 genetic variants on metabolism using a mouse model carrying a rare human genetic variant of SLC2A10 (GLUT10G128E mice); the study revealed that GLUT10G128E mice have impaired WAT development and are highly sensitive to HFD-induced obesity and metabolic dysregulation compared with WT mice [10].