HLA-C and cancer: MHC components HLA-A24, which preferentially presents tumour antigens with an aromatic residue at position 2 and a non-hydrophobic residue at the C-terminus, and HLA-B41, which displays self-peptides with Glu at position 2, were downregulated, whereas HLA-A69, associated with abnormal immune cell accumulation and suppression of the presentation of specific antigens, was upregulated; these factors all suggest a mechanism of immune avoidance by the cancer cells.