On the other hand, expression of the proapoptotic protein Bax in Nestin-Bax mice led to increased anxiety-like behaviour in the elevated plus maze and light/dark test but not in the novelty-suppressed feeding test74, whereas inducible expression of the Diptheria toxin A chain (DTA) in an inducible Nestin-Cre mice resulted in increased latency to eat in the novelty-suppressed feeding test but not in the light/dark test75. Here, NES is linked to Anxiety.