It can be concluded from the present study that ferulic acid demonstrated cardioprotection against cardiac oxidative damage and DCM by mitigating oxidative stress, lipid accumulation, and purinergic dysfunction, improving energy metabolism, and structural morphology while inhibiting ACE and acetylcholinesterase activities in cardiac tissues of T2D rats. The gene discussed is ACHE; the disease is familial dilated cardiomyopathy.