AGR2, PDE4D, and RAB15 may play some significant roles in cancer progression and functionally connect with action targets of the microtubulin disassembly inhibitor TXT, tubulin β chain genes such as TUBB2, TUBB3, TUBB4 and TUBB6 (Fig. 1 (A), Supplementary Dataset File 4). Here, TUBB3 is linked to cancer.