Because of the biological and clinical relevance of TAPBP methylation, which was correlated with melanoma-specific survival and RNA expression and concurred with other genome-wide deregulations that led to its high multi-OMICs driver potential, we performed technical validation of TAPBP methylation using bisulfite pyrosequencing in the BCH cohort (Supplementary Data 22). Here, TAPBP is linked to choreatic disease.