First, in the 39 case reports included, not all data pertaining to blood samples and clinical characteristics of AOSD severity scores were available for the parameters with the highest values (WBC, CRP, ferritin, and IL-18), as well as the clinical characteristics related to AOSD severity score (Table 2, Supplemental Digital Content, http://links.lww.com/MD/G881) listed in Table 1. This evidence concerns the gene IL18 and adult-onset Still disease.