CD8A and myeloid sarcoma: Interestingly, SARS-CoV-2 naïve anti-CD20-treated MS patients which induced the lowest antibody titers displayed the highest induction of activated CD8+ T cells after vaccination (Apostolidis et al., 2021; Brill et al., 2021; Gadani et al., 2021; Madelon et al., 2021).