CPS1 and lung adenocarcinoma: Projection of the CPS1 plus NAGS expression score onto TCGA squamous NSCLC confirmed that CPS1 plus NAGS expression was significantly lower in tumor compared with nontumor tissue, while a substantial proportion of lung adenocarcinoma tumors have low CPS1 plus NAGS expression compared with nontumor tissue (Supplemental Figure 4, K and L).