In the patient group, S1PR5 was correlated with diabetes, heart rate, triglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (ApoB), and fasting blood glucose (P < 0.05); CARNS1 was correlated with uric acid (UA) (P < 0.05). This evidence concerns the gene CARNS1 and diabetes mellitus.