PPP3CB and amyotrophic lateral sclerosis: RNAis against Pp2B-14D and CanA-14F (two fly orthologs of PPP3CB) exerted suppressive effects (Score = −3 for Pp2B-14D, Score = −2 for CanA-14F; Figure 2C and Table 3) on fly eye degeneration, which indicated that perturbation of PPP3CB had functional correlations with neurodegeneration in ALS.