TGFB2 and cancer: The TME has been shown to be crucial for tumor dormancy initiation and maintenance in breast cancer cells (Bakhshandeh et al., 2022) via paracrine/niche-related signaling [e.g., bone morphogenetic protein (BMP) 4 and 7 (Kobayashi et al., 2011; Gao et al., 2012), TGF-β2 (Bragado et al., 2013) and type 3 collagen (Di Martino et al., 2022)] that can maintain cancer cell dormancy in experimental models.