Reactivation of other dormancy factors, either autocrine [e.g., p38 MAPK (Aguirre-Ghiso et al., 2003), DYRK1A (Chen et al., 2013)] or paracrine/niche-related [e.g., BMP4 and 7 (Kobayashi et al., 2011; Gao et al., 2012), TGF-β2 (Bragado et al., 2013), type 3 collagen (Di Martino et al., 2022)] can maintain cancer cell dormancy in experimental models. The gene discussed is TGFB2; the disease is cancer.