S100A8 and neoplasm: As demonstrated in a mouse model, stress hormones (e.g., cortisol, epinephrine, norepinephrine, and serotonin) can awaken dormant tumor cells via the production of the pro-inflammatory proteins S100 calcium-binding protein A8 (S100A8) and S100A9 by neutrophils (Perego et al., 2020).