In contrast, the levels of IL-5, IL-22, IL-9, IL-31, TNF-β, GRO-α, RANTES, NGF-β in the aqueous humor were significantly lower in the CCH group than controls (P = 0.027, P = 0.008, P < 0.001, P = 0.004, P = 0.001, P = 0.002, P = 0.011, P = 0.005, respectively). This evidence concerns the gene CXCL1 and columnar cell hyperplasia of the breast.