Studies have indicated that myosteatosis is associated with insulin resistance, type 2 diabetes mellitus (T2DM), dyslipidemia and cardiometabolic diseases (17, 18), and there was also a link between skeletal muscle density and biomarkers of inflammation, such as CRP, IL-6, TNF-α, adiponectin and leptin (19). This evidence concerns the gene TNF and type 2 diabetes mellitus.