Malignant breast cancer cells (MCF10CA1a.cl1) expression of both CXCL7 and CXCR2 is higher than that of precancerous cells (MCF10AT), where MCF10AT transfected with CXCL7 were significantly more invasive through the basement membrane of the stroma, an effect that was markedly inhibited by the use of the CXCL7 antibody (Tang et al., 2008). Here, PPBP is linked to breast carcinoma.