Antiphospholipid syndrome (APS) is an autoimmune thrombotic disorder, has been associated with a significantly higher plasma levels of platelet activation-related chemokines CXCL4, CXCL7, and CCL5, suggesting a role for CXCL7 in APS thrombotic events (Patsouras et al., 2015). The gene discussed is PPBP; the disease is autoimmune polyendocrinopathy.