CXCR1 and nonpapillary renal cell carcinoma: In contrast, an inhibitor of the CXCL7 receptors CXCR1 and CXCR2 (SB225002) inhibited the proliferation of ccRCC cells and endothelial cells, thereby strongly suppressing tumor growth and aberrant tumor angiogenesis (Grépin et al., 2014).