The ROC curve was used to evaluate the clinical diagnostic efficacy of CXCL7 and other CRC tumor markers CEA, CA19-9, and CA125, and the results showed that CXCL7 had the highest diagnostic power, with an AUC of 0.862 (95% CI: 0.831–0.890) (Li et al., 2019), thus indicating that abnormal levels of CXCL7 may contribute to early detection and diagnosis of intestinal system tumors. Here, PPBP is linked to colorectal carcinoma.