PPBP and metastatic malignant neoplasm in the lymph nodes: Serum CXCL7 levels in OCRC patients have also been associated with stage N lymph node metastasis (N0-N2) and TNM stage (I-II to IV), and analysis of the multifactorial Cox proportional risk regression model analysis showed that high serum CXCL7 levels were an independent factor for poorer OS in OCRC patients (HR = 2.216, p = 0.032) (Li et al., 2019).