LEP and Insulin resistance: Van Hul et al. (2020) revealed, by analyzing both qPCR and shotgun metagenomic data, that the abundance of Subdoligranulum was correlated positively with microbial richness and HDL-cholesterol levels and negatively correlated with fat mass, adipocyte diameter, insulin resistance, levels of leptin, insulin, CRP, and IL-6 in humans.