Furthermore, our review of the literature did not reveal any reported case of a primary RMC tumor harboring an oncogenic TP53 mutation other than Case 10 from (10) (although in that case no detectable structural or copy number alterations involving the SMARCB1 locus could be detected), and a recent search also previously failed to identify any somatic mutation at the TP53 locus in MRT (37). This evidence concerns the gene TP53 and neoplasm.