The mutations that more frequently presented a correspondence between biopsy and plasma sample at T0 were located in the APC (9/15, 60%) and TP53 (14/22, 63%) genes, whereas minor correspondence was found concerning KRAS (3/9, 33%) genes and non-common CRC genes (2/9, 22%) (Figure 2). The gene discussed is KRAS; the disease is colorectal carcinoma.