ASIC1 and lung adenocarcinoma: Observed here, the lower expression of γ-ENaC in lung adenocarcinoma in comparison with normal lungs (Figure 9A) and the correlation of the increased γ-ENaC expression with worse survival prognosis (Figure 9C) may reflect the need to maintain the proper ratio between the ASIC homomers and ASIC1/α-ENaC/γ-ENaC heteromers in tumors and requires an additional detailed study.