FAT1 and gastric adenocarcinoma: Herein, to explore the relationship between FAT mutations and TMB or MSI, we evaluated the effect of TMB or MSI on the prognosis for FAT-WT and FAT-Mut patients and found that only when FAT mutated, TMB and MSI could stratify the benefits for patients, demonstrating that the effect of TMB and MSI on STAD prognosis depended on FAT mutations.