Comparing immune cells and immune-related gene expression across different FAT statuses, we found that in FAT mutant STAD, chemokines, such as CCL3, CCL4, CXCL1, CXCL3, CXCL9, and CXCL10, recruited and activated cytotoxic T lymphocytes in the tumor tissue to perform an antitumor effect. The gene discussed is CXCL1; the disease is neoplasm.