ADT modulates PD-L1 expression and CD8+ T-cells infiltration in the tumour microenvironment (Mercader et al., 2001; Gannon et al., 2009; Sorrentino et al., 2011; Agarwal et al., 2020; Antonarakis et al., 2020; Appleman et al., 2021; Fizazi et al., 2021). The gene discussed is CD8A; the disease is neoplasm.