Multiple logistic regression analysis as observed by Chi-square and regression coefficients identified increasing age (p = 0.027), smoking (p = 0.032), retinopathy (p = 0.013), eGFR (p = 0.024), HbA1C (p = 0.030) and inflammatory biomarkers like low levels of ApoA1 (p = 0.005) and IL-10 (p = 0.000) to be significantly associated with diabetic foot ulcers [Table 3]. The gene discussed is IL10; the disease is retinal disorder.