KRAS and colorectal cancer: Unsupervised clustering was also applied to each separate layer of omics data and showed that the average silhouette width of the subsets from the transcriptome, proteome, or phosphoproteome alone was smaller than that of the subsets from the integrated multi-omics (Figure 3C, Figure S3C), suggesting that integration of the three types of omics data could more accurately classify KRAS-Mut colorectal cancer.