KDM4C and leukemia: We found that the mRNA level of KDM4A was slightly decreased by SD49-7 in both THP-1 and MLL-AF9 leukemia cells (Figure S2B), whereas it decreased KDM4A and KDM4C protein levels only in THP-1 cells, but not in MLL-AF9 leukemia cells (Figure S2C-D).