The secretion levels of IFN-γ from pulmonary CD4+ and γδ T cells were increased in the BLM, NT127 and BLM/NT127 groups compared with the naïve group, but the percentages and numbers of IFN-γ+CD4+ and IFN-γ+ γδ T cells did not differ significantly among the BLM, NT127 and BLM/NT127 groups. The gene discussed is IFNG; the disease is Bloom syndrome.