Similarly, the YAP1 level in the tumor tissues derived from the CLP36 knockdown primary p53 KO sarcoma cells, which expressed a much lower level of YAP1 than those expressing a normal level of CLP36 (Figure 5G, compare lane 3 with lanes 1 and 2), was also significantly reduced compared with those derived from the control p53 KO sarcoma cells (Figure 5H). The gene discussed is TP53; the disease is neoplasm.