Similar results were also observed in several distinct mouse models of AKI, including IRI-AKI, cis-platinum-induced AKI (CIS-AKI), and folic acid-induced AKI (FA-AKI) (Figure 1B and Figure S1C-E), indicating that loss-of-DUSP2 in RTECs was a common characteristic of AKI. This evidence concerns the gene DUSP2 and acute kidney injury.