SOX30 and neoplasm: For instance, SOX30 is able to repress tumor metastasis in lung cancer by regulating the Wnt signaling pathway (8); SOX30 also plays an anti-metastatic role in ovarian cancer through modulating the epithelial-mesenchymal transition (EMT) process (9); it has been illustrated that SOX30 has the capacity of inhibiting proliferation and invasion but promoting apoptosis of T24 and 5,673 cells to suppress the progression of bladder cancer (12).