For example, CCL14, CBX3/HP1, APEX1, and UBE2C are considered to be prognostic biomarkers for HCC (Wei Z. et al., 2019; Zhong X. et al., 2019; Cao et al., 2020; Gu et al., 2020). The gene discussed is UBE2C; the disease is hepatocellular carcinoma.