Wu et al. found that down-regulation of METTL14 inhibit the expression of scavenger receptor B-type 1 (SR-B1) by downregulating the m6A methylation of SR-B1 mRNA, and further reduces cholesterol efflux and promotes foam cell formation, aggravating lipid metabolism disorder (Wu et al., 2021; Table 3 and Figure 2). The gene discussed is SCARB1; the disease is Disorder of lipid metabolism.