In accordance with the expression and coefficient of candidate genes (Table 3), we developed an EMT-derived prognostic model for osteosarcoma, comprising RPS9, RPS23, EIF4A1, RPL12, RPL36, RPL37A, RPL34, EEF1B2, RPS8, RPS28, RPL10, RPS24, RPL35A, RPL11, RPL21, RPS27A, RPS12, and RPL13A. Here, RPS9 is linked to osteosarcoma.