Univariate Cox regression analysis identified the following factors that affected PFS: tumour lesion number < 3 (OR 0.428, 95% CI, 0.187–0.982; P = 0.045), AFP level < 400 ng/mL (OR 0.448, 95% CI, 0.227–0.883; P = 0.020), and TBIL (OR 1.036, 95% CI, 1.006–1.066; P = 0.018). The gene discussed is AFP; the disease is neoplasm.